This text incorporates paid for content material produced in collaboration with Arvia Technology.
Lively Pharmaceutical Substances (APIs) are notoriously tough to take away from wastewater. Conventional water remedy techniques don’t simply take away APIs from water, so pharmaceutical firms typically should resort to high-cost incineration as a substitute.
Shopper: International Pharmaceutical Firm
A well known pharma firm approached Arvia due to the precise state of affairs above. The present disposal answer was incineration however they wished to discover a higher answer which was not as expensive, both financially or to the surroundings.
Drawback: To scale back 4 APIs to PNEC ranges
The pharma big wanted to take away 4 APIs: ibrutinib, topiramate, rilpivirine (TMC278) and paliperidone palmitate. All 4 APIs needed to be lowered to under PNEC ranges (Predicted No-Impact Focus). No conventional water remedy techniques had been in a position to do that, so the pharma firm had to take a look at new know-how.
Answer
Arvia Expertise specialises in electrochemical oxidation for elimination of persistent natural compounds from industrial wastewater. The vary known as Nyex, and they’re all based mostly on a super-efficient electrochemical oxidation course of, both with or with out an integral adsorption course of in the identical unit.
For this challenge, Nyex Ellenox adopted by Nyex Rosalox lowered all 4 APIs to under PNEC values. To see how the Rosalox works, see this brief animation:
And for an outline of the merchandise see: https://arviatechnology.com/water-treatment-products/
End result
Nyex Ellenox and Nyes Rosalox together was proven to take away all 4 APIs to under the required ranges which meant the pharma firm may keep away from the prices of incineration
- Topiramate 1000μg/L
- Ibrutinib 1.55μg/L
- Ripilvirine 2.0μg/L
- Paliperidone palmitate 250 μg/L
Arvia’s CEO, Simon Gatcliffe mentioned, “Our client had budgeted for 1000 tonnes per year to be incinerated, which equates to about 460,000 Euros. Our solution represents a very strong ROI.”
